SCHEMBL7904166

SCHEMBL7904166

Nc1cnc(O)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23114264 0.72 MEN1 (0.43)
SCHEMBL1080070 0.72
SCHEMBL2495212 0.72
SCHEMBL581425 0.67
SCHEMBL30912672 0.67
SCHEMBL254689 0.67
SCHEMBL2307928 0.67
SCHEMBL1274799 0.67
SCHEMBL20886066 0.67
SCHEMBL9779663 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115915942-A Selective herbicides based on substituted isoxazoline carboxamides and mefenpyr-diethyl 拜耳公司 2023-04-04 CN disclosed
CN-115697062-A Selective herbicides based on substituted isoxazoline carboxamides and bisbenzoxazoic acids 拜耳公司 2023-02-03 CN disclosed
CN-115666244-A Selective herbicides based on substituted isoxazoline carboxamides and cloquintocet-mexyl 拜耳公司 2023-01-31 CN disclosed
US-20210113449-A1 HAIR DYEING METHOD USING A DYE COMPOSITION AND AN OXIDIZING COMPOSITION, SAID COMPOSITIONS COMPRISING A SCLEROGLUCAN GUM L'OREAL (FR) 2021-04-22 US disclosed
CN-103709731-A Quantum dot/polyurethane nano crystal complex and preparation method thereof as well as colorful conversion film TCL GROUP CO LTD 2014-04-09 CN disclosed
CN-102256493-A Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities DECIPHERA PHARMACEUTICALS LLC 2011-11-23 CN disclosed
WO-2010111634-A2 RENIN INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-09-30 WO disclosed
CN-101370801-A Novel cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors AVENTIS PHARMA SA (FR) 2009-02-18 CN disclosed
CN-101128454-A Pyridine carboxamide derivatives for use as anticancer agents ASTRAZENECA AB (SE) 2008-02-20 CN disclosed
CN-1326519-C Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK AS (DK) 2007-07-18 CN disclosed
CN-1602191-A Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK AS (DK) 2005-03-30 CN disclosed
US-5036068-A Cardiovascular disorders MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-07-30 US disclosed
EP-0371312-A1 Benzoxazine derivatives MERCK PATENT GmbH (DE) 1990-06-06 EP disclosed