Oxyquinoline

Oxyquinoline

SCHEMBL7904185

[Al+3].[Al].[O-]c1cccc2cccnc12.[O-]c1cccc2cccnc12.[O-]c1cccc2cccnc12

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
LMNA P02545 3/20 0.56
MAPT P10636 3/20 0.56
MMP2 P08253 2/20 0.56
TSHR P16473 2/20 0.56
CYP3A4 P08684 2/20 0.56
ALOX15 P16050 2/20 0.56
HTT P42858 2/20 0.56
CCR1 P32246 2/20 0.56
CCR5 P51681 2/20 0.56
CCR8 P51685 2/20 0.56
GMNN O75496 1/20 0.56
TP53 P04637 1/20 0.56
HSP90AA1 P07900 1/20 0.56
CYP2D6 P10635 1/20 0.56
MMP9 P14780 1/20 0.56
NFKB1 P19838 1/20 0.56
MMP8 P22894 1/20 0.56
THPO P40225 1/20 0.56
MTOR P42345 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL30010853 0.98 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL61235 0.98 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL296880 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL22660883 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL3357860 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL23175212 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL2873348 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL8537748 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL23091400 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR
Oxyquinoline SCHEMBL543361 0.93 KDM4E (0.58) KDM4ELMNAMAPTMMP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6333065-B1 Process for the production of an organic electroluminescent device TDK CORPORATION (JP) 2001-12-25 US disclosed