Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 3/20 | 0.58 |
| ▸ | CCR8 | P51685 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL460412 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL952769 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL3357860 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL23091400 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL2873348 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL23175212 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL296880 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL543361 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL22660883 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL61235 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |
| EP-0892587-A2 | Organic EL device and method for production thereof | TDK Corporation (JP) | 1999-01-20 | — | — | EP | disclosed |