Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL427902 | 0.98 | SLC6A2 (0.42) | CYP2D6SRCDPP4ATML3MBTL1 | |
| SCHEMBL8332384 | 0.87 | LMNA (0.40) | CYP2D6SRCDPP4ATML3MBTL1 | |
| SCHEMBL8332386 | 0.87 | LMNA (0.40) | CYP2D6SRCDPP4ATML3MBTL1 | |
| SCHEMBL7899034 | 0.85 | BLM (0.45) | CYP2D6SRCLMNASLC1A2SLC1A3 | |
| SCHEMBL10656849 | 0.85 | BLM (0.45) | CYP2D6SRCLMNASLC1A2SLC1A3 | |
| SCHEMBL6022367 | 0.81 | CYP2D6 (0.43) | CYP2D6SRCDPP4LMNAMAPK1 | |
| SCHEMBL503603 | 0.81 | CYP2D6 (0.43) | CYP2D6SRCDPP4LMNAMAPK1 | |
| SCHEMBL503566 | 0.81 | CYP2D6 (0.43) | CYP2D6SRCDPP4LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL28324487 | 0.79 | CYP2D6 (0.42) | CYP2D6SRCDPP4LMNAMAPK1 | |
| SCHEMBL29185562 | 0.78 | LMNA (0.48) | CYP2D6SRCATML3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |
| US-6140100-A | CONJUGATE POLYPEPTIDE WHICH IS TISSUE PREFERENTIAL; ANTICARCINOGENIC AGENTS | GLAXO WELLCOME INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0728018-A1 | THERAPY | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013095-A2 | THERAPY | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |