Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905544 | 0.74 | CETP (0.43) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL2550650 | 0.71 | NPC1 (0.54) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL11217076 | 0.70 | NPC1 (0.55) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL4619856 | 0.70 | NPC1 (0.56) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL11594363 | 0.69 | POLB (0.57) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL27773069 | 0.69 | NPC1 (0.54) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL8747480 | 0.68 | KDM4E (0.42) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5286578 | 0.68 | HPGD (0.49) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL6960073 | 0.68 | NPC1 (0.53) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL236205 | 0.68 | HPGD (0.56) | NPC1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194443-B1 | Aminophenol derivatives with fungicidal property | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |