SCHEMBL236205

SCHEMBL236205

COC(=O)Cc1cccs1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.56
ALDH1A1 P00352 2/20 0.56
SMN1; SMN2 Q16637 4/20 0.55
NPC1 O15118 5/20 0.54
KMT2A Q03164 4/20 0.54
RAB9A P51151 4/20 0.54
L3MBTL1 Q9Y468 4/20 0.54
MEN1 O00255 3/20 0.54
POLB P06746 3/20 0.54
BLM P54132 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
MAPK8 P45983 1/20 0.54
MAPK9 P45984 1/20 0.54
MAPK10 P53779 1/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
CYP2C19 P33261 2/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL29448975 0.96 HPGD (0.53) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
Dodecane SCHEMBL5901080 0.90 ALDH1A1 (0.56) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
SCHEMBL11217076 0.84 NPC1 (0.55) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
SCHEMBL4461404 0.83 SMN1; SMN2 (0.51) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL30402639 0.83 ALDH1A1 (0.44) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
SCHEMBL358221 0.81 POLB (0.60) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
SCHEMBL11217079 0.81 NPC1 (0.50) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
SCHEMBL20464033 0.81 L3MBTL1 (0.50) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
SCHEMBL1200934 0.81 HPGD (0.53) HPGDALDH1A1SMN1; SMN2NPC1KMT2A
Hydrochloric Acid SCHEMBL8763040 0.81 SMN1; SMN2 (0.50) HPGDALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119120633-A Method for preparing cefalonine by using enzymatic method 珠海联邦制药股份有限公司 2024-12-13 CN claimed
CN-111033835-A Polymer material for lithium secondary battery and method for producing same 株式会社LG化学 2020-04-17 CN claimed
CN-104447800-B A kind of synthetic technology of cefoxitin acid 辽宁天华生物药业有限公司 2016-11-16 CN claimed
CN-105742709-A Lithium ion battery electrolyte and lithium ion battery using same 东莞市杉杉电池材料有限公司 2016-07-06 CN claimed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP claimed
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2026-04-23 US disclosed
EP-4673137-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME Sionna Therapeutics Inc. (US) 2026-01-07 EP disclosed
EP-4653436-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF GUANGZHOU YUFAN NANTU BIOTECHNOLOGIES CO., LTD (CN) 2025-11-26 EP disclosed
US-12448355-B2 Acetyl-CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2025-10-21 US disclosed
EP-4044284-B1 CATHODE ACTIVE MATERIAL FOR LITHIUM-SULFUR BATTERY, PREPARATION METHOD THEREFOR, AND LITHIUM-SULFUR BATTERY COMPRISING SAME LG ENERGY SOLUTION LTD (KR) 2025-10-01 EP disclosed
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
WO-2025072151-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF BAYLOR UNIVERSITY (US) 2025-04-03 WO disclosed
US-4237298-A Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1980-12-02 US disclosed
US-4153610-A Process for producing 5-carboxy-2-acetylthiophene SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-05-08 US disclosed
US-4144248-A Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1979-03-13 US disclosed
US-4130566-A Process for producing 5-carboxy-2-acetylthiophene SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-12-19 US disclosed
US-4107178-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1978-08-15 US disclosed
US-4086420-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-04-25 US disclosed
US-4051151-A Thiophene derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-09-27 US disclosed
US-3965099-A Cephalosporin esters with antibacterial activity SMITHKLINE CORPORATION (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12448355-B2 Acetyl-CoA carboxylase modulators ACACA, ACACB, ACAT2 HPGD 800/4885ALDH1A1 1039/4885SMN1; SMN2 4874/4885
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, HACL2 HPGD 1847/4885ALDH1A1 1026/4885SMN1; SMN2 4878/4885
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES TAS1R3, TAS2R5, TRPA1 HPGD 479/4885ALDH1A1 117/4885SMN1; SMN2 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.