SCHEMBL7904269

SCHEMBL7904269

CC(F)CCCCCOS(C)(=O)=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
ALDH1A1 P00352 2/20 0.60
KDM4E B2RXH2 1/20 0.60
USP2 O75604 1/20 0.60
LMNA P02545 1/20 0.60
MMP9 P14780 1/20 0.60
ALOX15 P16050 1/20 0.60
CA1 P00915 16/20 0.37
CA2 P00918 16/20 0.37
CA9 Q16790 15/20 0.37
CA12 O43570 5/20 0.37
CA7 P43166 5/20 0.37
CA14 Q9ULX7 5/20 0.37
CA3 P07451 4/20 0.37
CA4 P22748 4/20 0.37
CA6 P23280 4/20 0.37
CA5A P35218 4/20 0.37
CA5B Q9Y2D0 4/20 0.37
RECQL P46063 2/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911648 0.98 TSHR (0.62) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL10081545 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL29492180 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL12354861 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL8860696 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL11400795 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL3084957 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL18419074 0.83 LMNA (0.65) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL6484412 0.81 LMNA (0.68) TSHRALDH1A1KDM4EUSP2LMNA
SCHEMBL7911585 0.81 TSHR (0.56) TSHRALDH1A1KDM4EUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100338175-C Chiral liquid crystal compounds having fluorine-containing terminal moieties MINNESOTA MINING & MFG (US) 2007-09-19 CN disclosed
CN-1326494-A Chiral liquid crystal compounds having fluorinated terminal portion MINNESOTA MINING & MFG (US) 2001-12-12 CN disclosed
EP-1135450-A1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A FLUORINATED TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2001-09-26 EP disclosed
US-6139924-A CONTAINING A PYRIMIDINE RING 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-31 US disclosed
WO-2000031210-A1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A FLUORINATED TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-06-02 WO disclosed