Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345560 | 0.90 | ADORA1 (0.64) | ADORA1ADORA3SMN1; SMN2P2RY11DNPH1 | |
| SCHEMBL7906331 | 0.89 | ADORA1 (0.54) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL7896942 | 0.84 | ADORA1 (0.55) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL7902980 | 0.84 | ADORA1 (0.51) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL12376383 | 0.84 | ADORA3 (0.64) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL12360837 | 0.84 | ADORA3 (0.64) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL8626012 | 0.84 | ADORA3 (0.64) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL21999233 | 0.84 | ADORA3 (0.64) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL7708744 | 0.83 | ADORA3 (0.55) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 | |
| SCHEMBL7708739 | 0.83 | ADORA3 (0.55) | ADORA1ADORA3RNASELSMN1; SMN2P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37077-E1 | Adenosine derivatives and pharmaceutical composition thereof | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |