Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL790445

C=CCOP(=O)(O)OCC.N

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.38
BTN3A1 O00481 2/20 0.37
TSHR P16473 3/20 0.37
TDP1 Q9NUW8 2/20 0.34
TP53 P04637 1/20 0.34
LPAR3 Q9UBY5 2/20 0.33
LPAR2 Q9HBW0 1/20 0.33
FNTA P49354 4/20 0.33
FNTB P49356 4/20 0.33
PGGT1B P53609 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366766 0.98 PPARD (0.39) PPARDBTN3A1TSHRTDP1TP53
SCHEMBL6251753 0.90 BTN3A1 (0.44) PPARDBTN3A1TSHRTDP1TP53
Ammonia Solution, Strong SCHEMBL8023938 0.89 BTN3A1 (0.39) BTN3A1TSHRLPAR3LPAR2FNTA
SCHEMBL174096 0.87 BTN3A1 (0.40) BTN3A1TSHRLPAR3LPAR2FNTA
Diethyl Hydrogen Phosphate SCHEMBL9069052 0.85 TSHR (0.42) PPARDBTN3A1TSHRTDP1TP53
SCHEMBL10625461 0.84 BTN3A1 (0.39) BTN3A1TSHRLPAR3LPAR2FNTA
SCHEMBL11677557 0.84 BTN3A1 (0.39) BTN3A1TSHRLPAR3LPAR2FNTA
Ethylene SCHEMBL28068723 0.84 BTN3A1 (0.39) BTN3A1TSHRLPAR3LPAR2FNTA
Dimethylamine SCHEMBL27846578 0.83 BTN3A1 (0.39) BTN3A1LPAR3LPAR2FNTAFNTB
Sulfotep SCHEMBL2828854 0.82 PPARD (0.35) PPARDBTN3A1TSHRTDP1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586066-B2 Topical antifungal composition DELCOR ASSET CORPORATION (US) 2013-11-19 US disclosed
US-20120070384-A1 TOPICAL ANTIFUNGAL COMPOSITION STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2012-03-22 US disclosed
US-20110251146-A1 TOPICAL ANTIFUNGAL COMPOSITION STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2011-10-13 US disclosed
US-8026238-B2 Topical antifungal composition Stiefel Research Australia, Pty Ltd (AU) 2011-09-27 US disclosed
US-7553835-B1 Topical antifungal composition STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2009-06-30 US disclosed
US-20090149473-A1 Topical antifungal composition STIEFEL RESEARCH AUSTRALIA PTY LTD. (AU) 2009-06-11 US disclosed
EP-1024792-B1 TOPICAL ANTIFUNGAL COMPOSITION CONNETICS AUSTRALIA PTY LTD (AU) 2006-11-29 EP disclosed
EP-1692951-A1 Topical antifungal composition Connetics Australia Pty Limited (AU) 2006-08-23 EP disclosed
EP-1024792-A4 TOPICAL ANTIFUNGAL COMPOSITION SOLTEC RES PTY LTD (AU) 2001-08-08 EP disclosed
EP-1024792-A1 TOPICAL ANTIFUNGAL COMPOSITION SOLTEC RESEARCH PTY. LTD. (AU) 2000-08-09 EP disclosed
WO-1999020250-A1 TOPICAL ANTIFUNGAL COMPOSITION SOLTEC RESEARCH PTY. LTD. (AU) 1999-04-29 WO disclosed