SCHEMBL366766

SCHEMBL366766

C=CCOP(=O)(O)OCC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.39
TSHR P16473 3/20 0.39
BTN3A1 O00481 2/20 0.38
TDP1 Q9NUW8 2/20 0.36
TP53 P04637 1/20 0.36
LPAR3 Q9UBY5 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34
FNTA P49354 4/20 0.33
FNTB P49356 4/20 0.33
PGGT1B P53609 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL790445 0.98 PPARD (0.38) PPARDTSHRBTN3A1TDP1TP53
SCHEMBL6251753 0.92 BTN3A1 (0.44) PPARDTSHRBTN3A1TDP1TP53
SCHEMBL174096 0.89 BTN3A1 (0.40) TSHRBTN3A1LPAR3LPAR2FNTA
Ethylene SCHEMBL28068723 0.86 BTN3A1 (0.39) TSHRBTN3A1LPAR3LPAR2FNTA
Ammonia Solution, Strong SCHEMBL8023938 0.86 BTN3A1 (0.39) TSHRBTN3A1LPAR3LPAR2FNTA
SCHEMBL11677557 0.86 BTN3A1 (0.39) TSHRBTN3A1LPAR3LPAR2FNTA
SCHEMBL10625461 0.86 BTN3A1 (0.39) TSHRBTN3A1LPAR3LPAR2FNTA
Dimethylamine SCHEMBL27846578 0.84 BTN3A1 (0.39) BTN3A1LPAR3LPAR2FNTAFNTB
Sulfotep SCHEMBL2828854 0.84 PPARD (0.35) PPARDTSHRBTN3A1TDP1FNTA
SCHEMBL4641076 0.83 LPAR3 (0.36) TSHRBTN3A1LPAR3LPAR2FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042487-B2 Method for reducing side effects from administration of phosphodiesterase-4 inhibitors ARCUTIS BIOTHERAPEUTICS, INC. (US) 2024-07-23 US claimed
EP-4375419-A2 METHOD OF MANUFACTURING A MULTI-RING CAN-HOLDER E6PR S.A.P.I DE C.V. (MX) 2024-05-29 EP claimed
US-20240024300-A1 METHOD FOR REDUCING SIDE EFFECTS FROM ADMINISTRATION OF PHOSPHODIESTERASE-4 INHIBITORS ARCUTIS BIOTHERAPEUTICS, INC. (US) 2024-01-25 US claimed
WO-2023083325-A1 FLAME RETARDANT AND USE THEREOF, AND FIRE-RESISTANT EPOXY RESIN 北京深云智合科技有限公司 2023-05-19 WO claimed
CN-116120634-A Flame retardant, application thereof and fire-resistant epoxy resin 北京深云智合科技有限公司 2023-05-16 CN claimed
CN-116120885-A Adhesive, and preparation method and application thereof 北京深云智合科技有限公司 2023-05-16 CN claimed
CN-115322309-B Organosilicon acrylic emulsion and preparation method and application thereof 广州海豚新材料有限公司 2023-05-09 CN claimed
CN-115322309-A Organosilicon acrylic emulsion and preparation method and application thereof 广州海豚新材料有限公司 2022-11-11 CN claimed
CN-112746347-A Preparation method of halogen-free flame-retardant polyacrylonitrile fiber 中国石油化工股份有限公司 2021-05-04 CN claimed
CN-109790277-B Polyisocyanate composition, blocked polyisocyanate composition, coating composition, aqueous coating composition and coated substrate 旭化成株式会社 2021-04-23 CN claimed
CN-105255159-A Cured track bed sinking repairing high-viscosity vibration attenuation polyurethane repairing material RAILWAY ENG RES INST CHINA ACADEMY RAILWAY SCIENCE 2016-01-20 CN claimed
EP-1373447-B1 A METHOD FOR REMOVING POLYMER FILMS IN THE MANUFACTURE OF AQUEOUS COMPOSITIONS CONTAINING ACRYLATES COPOLYMER P & G CLAIROL INC (US) 2011-01-19 EP claimed
EP-1383859-B1 A METHOD FOR REMOVING POLYMER FILMS IN THE MANUFACTURE OF AQUEOUS COMPOSITIONS CONTAINING ANIONIC AMPHIPHILIC POLYMERS P & G CLAIROL INC (US) 2011-01-19 EP claimed
CN-100471393-C Agrochemical composition SYNGENTA LTD (GB) 2009-03-25 CN claimed
CN-100471391-C Agrochemical compositions SYNGENTA LTD (GB) 2009-03-25 CN claimed
US-6984268-B2 Method for removing polymer films in the manufacture of aqueous compositions containing anionic amphiphilic polymers THE PROCTER & GAMBLE COMPANY (US) 2006-01-10 US claimed
US-6936113-B2 Method for removing polymer films in the manufacture of aqueous compositions containing acrylates copolymer THE PROCTER & GAMBLE COMPANY (US) 2005-08-30 US claimed
US-20020183221-A1 Method for removing polymer films in the manufacture of aqueous compositions containing acrylates copolymer WELLA OPERATIONS US, LLC 2002-12-05 US claimed
US-20020160923-A1 Method for removing polymer films in the manufacture of aqueous compositions containing anionic amphiphilic polymers NOXELL CORPORATION 2002-10-31 US claimed
US-5330622-A Applying glyoxal, dimeric alkylketene and diethanolamine salt of perfluoroalkyl ethyl phosphate to base with aid of impregnating press AUSSEDAT-REY (FR) 1994-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12042487-B2 Method for reducing side effects from administration of phosphodiesterase-4 inhibitors PDE12, PDE4A, SMPD4 PPARD 1432/4885TSHR 3003/4885BTN3A1 4692/4885
US-20240024300-A1 METHOD FOR REDUCING SIDE EFFECTS FROM ADMINISTRATION OF PHOSPHODIESTERASE-4 INHIBITORS PDE12, PDE4A, SMPD4 PPARD 1432/4885TSHR 3003/4885BTN3A1 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.