Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896515 | 0.90 | HTR1B (0.38) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| SCHEMBL7896441 | 0.88 | HTR1B (0.37) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| SCHEMBL7902642 | 0.88 | HTR1B (0.36) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7903914 | 0.88 | HTR1B (0.36) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| SCHEMBL7904622 | 0.86 | HRH3 (0.39) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| SCHEMBL7903964 | 0.85 | HTR1B (0.34) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| SCHEMBL7902674 | 0.85 | HRH3 (0.40) | HTR1BKDM4EHTR7HRH3ATM | |
| SCHEMBL7896510 | 0.85 | CACNA1B (0.40) | HTR1BKDM4EHTR7HRH3HRH1 | |
| SCHEMBL7908461 | 0.84 | HRH1 (0.37) | HTR1BKDM4EHTR7HRH3ALDH1A1 | |
| SCHEMBL7903918 | 0.84 | ATM (0.34) | HTR1BKDM4EHTR7HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |