Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903964 | 0.89 | HTR1B (0.34) | HRH3KDM4EHTR7ADRB2ADRB1 | |
| SCHEMBL7904676 | 0.89 | RAB9A (0.33) | PAK4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7896441 | 0.88 | HTR1B (0.37) | HRH1HRH3KDM4EHTR7ADRB2 | |
| Hydrochloric Acid SCHEMBL7903914 | 0.88 | HTR1B (0.36) | HRH1HRH3KDM4EHTR7ADRB2 | |
| SCHEMBL7908493 | 0.87 | HTR1B (0.33) | HRH1HRH3KDM4EHTR7ADRB2 | |
| SCHEMBL7903818 | 0.87 | ATM (0.34) | HRH1HRH3KDM4EHTR7ADRB2 | |
| SCHEMBL7908544 | 0.87 | KDM4E (0.34) | HRH3KDM4EHTR7ADRB2ADRB1 | |
| SCHEMBL7904672 | 0.84 | HTR1B (0.39) | HRH1HRH3KDM4EHTR7ADRB2 | |
| SCHEMBL7905806 | 0.84 | HTR7 (0.40) | KDM4EHTR7ADRB2ADRB1HTR1B | |
| SCHEMBL7896510 | 0.83 | CACNA1B (0.40) | HRH1HRH3KDM4EHTR7HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |