Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904228 | 0.91 | NPC1 (0.39) | MEN1POLBKMT2AERAP1ALDH1A1 | |
| SCHEMBL7903324 | 0.90 | NPC1 (0.41) | POLBALDH1A1KDM4EGLAGAA | |
| SCHEMBL7899046 | 0.84 | ALDH1A1 (0.41) | MEN1POLBKMT2AERAP1ALDH1A1 | |
| SCHEMBL7906217 | 0.84 | TP53 (0.39) | POLBALDH1A1KDM4EGLAGAA | |
| SCHEMBL7897320 | 0.78 | NPC1 (0.43) | MEN1POLBKMT2AERAP1ALDH1A1 | |
| SCHEMBL3467749 | 0.76 | HSD17B13 (0.37) | MEN1POLBKMT2AALDH1A1KCNH2 | |
| SCHEMBL7904657 | 0.76 | NPC1 (0.42) | MEN1KMT2AALDH1A1KDM4EGLA | |
| SCHEMBL7902906 | 0.75 | NPC1 (0.45) | MEN1POLBKMT2AERAP1ALDH1A1 | |
| SCHEMBL7903482 | 0.74 | HSD17B13 (0.37) | MELK | |
| SCHEMBL7899042 | 0.74 | HSD17B13 (0.35) | ERAP1ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071944-A1 | QUINAZOLINONE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2010-07-01 | — | — | WO | disclosed |