⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furfuryl Alcohol SCHEMBL1436757 | 0.97 | ALDH1A1 (0.47) | — | |
| Furfuryl Alcohol SCHEMBL37326 | 0.97 | — | — | |
| Furfuryl Alcohol SCHEMBL1260532 | 0.95 | — | — | |
| Furfuryl Alcohol SCHEMBL11661258 | 0.95 | ALDH1A1 (0.45) | — | |
| Furfuryl Alcohol SCHEMBL16415764 | 0.95 | — | — | |
| Furfuryl Alcohol SCHEMBL29092545 | 0.95 | — | — | |
| Furfuryl Alcohol SCHEMBL30524190 | 0.95 | — | — | |
| Furfuryl Alcohol SCHEMBL11661252 | 0.95 | — | — | |
| Furfuryl Alcohol SCHEMBL6417594 | 0.95 | — | — | |
| Furfuryl Alcohol SCHEMBL27982438 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |