SCHEMBL790494

SCHEMBL790494

CC(N)N1CCNCC1.NCCN1CCNCC1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ANPEP P15144 1/20 0.36
ERAP2 Q6P179 1/20 0.36
CXCR4 P61073 2/20 0.36
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
SIGMAR1 Q99720 3/20 0.32
RAD52 P43351 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16266915 0.85 SMN1; SMN2 (0.39) SMN1; SMN2POLBHSD17B10ANPEPERAP2
SCHEMBL11051675 0.82 ALOX15 (0.59) ALOX15SMN1; SMN2SIGMAR1ALDH1A1
SCHEMBL8765274 0.82
SCHEMBL17210 0.82
SCHEMBL17209 0.82
SCHEMBL790495 0.82 ALOX15 (0.63) ALOX15SMN1; SMN2POLBHSD17B10ANPEP
SCHEMBL7784004 0.82
SCHEMBL28155645 0.82 MEN1 (0.37) SMN1; SMN2CHRM5CHRM3SIGMAR1MEN1
SCHEMBL29143564 0.81 ALOX15 (0.43) ALOX15SMN1; SMN2POLBHSD17B10ANPEP
SCHEMBL9317238 0.81 ALOX15 (0.48) ALOX15SMN1; SMN2POLBHSD17B10ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970718-B1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-04-22 EP disclosed
EP-2616520-B1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2018-02-21 EP disclosed
US-8981027-B2 Two-part, cyanoacrylate/cationically curable adhesive systems Henkel IP & Holding GmbH (DE) 2015-03-17 US disclosed
US-20140275419-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS HENKEL IRELAND LIMITED (DE) 2014-09-18 US disclosed
US-8742048-B2 Two-part, cyanoacrylate /cationically curable adhesive systems Henkel IP & Holding GmbH (DE) 2014-06-03 US disclosed
US-8580888-B2 Two-part, cyanoacrylate/cationically curable adhesive systems HENKEL IRELAND LIMITED (DE) 2013-11-12 US disclosed
EP-2616520-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel Ireland Limited (DE) 2013-07-24 EP disclosed
US-20130178560-A1 TWO-PART, CYANOACRYLATE /CATIONICALLY CURABLE ADHESIVE SYSTEMS HENKEL IRELAND LIMITED (IE) 2013-07-11 US disclosed
US-20130053497-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS HENKEL IRELAND LTD. (IE) 2013-02-28 US disclosed
WO-2012035112-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS LOCTITE (R&D) LIMITED (IE) 2012-03-22 WO disclosed