SCHEMBL7905023

SCHEMBL7905023

COC(c1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1)c1ccc(-c2cccc(F)c2)o1.[LiH]

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 16/20 0.60
FNTB P49356 16/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910417 0.91 FNTA (0.61) FNTAFNTB
SCHEMBL7904947 0.91 FNTA (0.55) FNTAFNTB
SCHEMBL7905718 0.91 FNTA (0.61) FNTAFNTB
SCHEMBL7907104 0.90 FNTA (0.58) FNTAFNTB
SCHEMBL8588100 0.90 FNTA (0.62) FNTAFNTB
SCHEMBL8590218 0.90 FNTA (0.56) FNTAFNTB
SCHEMBL7910523 0.90 FNTA (0.59) FNTAFNTB
SCHEMBL7903829 0.90 FNTA (0.60) FNTAFNTB
SCHEMBL8590275 0.90 FNTA (0.58) FNTAFNTB
SCHEMBL8589227 0.90 FNTA (0.58) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed