SCHEMBL7907104

SCHEMBL7907104

COC(c1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1)c1ccc(-c2ccccc2F)o1.[LiH]

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 14/20 0.58
FNTB P49356 14/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8589227 0.99 FNTA (0.58) FNTAFNTB
SCHEMBL7905988 0.90 FNTA (0.59) FNTAFNTB
SCHEMBL7905023 0.90 FNTA (0.60) FNTAFNTB
SCHEMBL7904947 0.90 FNTA (0.55) FNTAFNTB
SCHEMBL8592287 0.90 FNTA (0.60) FNTAFNTB
SCHEMBL8590218 0.89 FNTA (0.56) FNTAFNTB
SCHEMBL7897459 0.89 FNTA (0.55) FNTAFNTB
SCHEMBL7910523 0.89 FNTA (0.59) FNTAFNTB
SCHEMBL7903829 0.89 FNTA (0.60) FNTAFNTB
SCHEMBL8590275 0.89 FNTA (0.58) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed