Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.67 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17768259 | 0.85 | TARBP2 (0.82) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4918154 | 0.81 | TARBP2 (1.00) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17768132 | 0.81 | TARBP2 (0.74) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7907774 | 0.80 | TARBP2 (0.82) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28295527 | 0.79 | TARBP2 (1.00) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28295518 | 0.79 | TARBP2 (1.00) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11623692 | 0.79 | TARBP2 (0.80) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28297264 | 0.79 | TARBP2 (1.00) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7908257 | 0.79 | TARBP2 (0.64) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2485336 | 0.79 | TARBP2 (0.94) | TARBP2PDCD4KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |