Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 5/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12957364 | 0.94 | BCL2 (0.69) | BCL2MCL1MEN1KMT2ACDC25B | |
| SCHEMBL1038715 | 0.94 | BCL2 (0.80) | BCL2MCL1MEN1KMT2ACDC25B | |
| SCHEMBL8653360 | 0.89 | BCL2 (0.73) | BCL2MCL1MEN1KMT2ACDC25B | |
| SCHEMBL12956976 | 0.89 | BCL2 (0.76) | BCL2MCL1MEN1KMT2ACDC25B | |
| SCHEMBL9925983 | 0.87 | BCL2 (0.77) | BCL2MCL1MEN1KMT2ANPC1 | |
| SCHEMBL9738860 | 0.85 | BCL2 (0.73) | BCL2MCL1MEN1KMT2ACDC25B | |
| SCHEMBL11546722 | 0.84 | BCL2 (0.62) | BCL2MCL1MEN1KMT2ANPC1 | |
| SCHEMBL14780791 | 0.84 | BCL2 (0.62) | BCL2MCL1MEN1KMT2ANPC1 | |
| SCHEMBL11294862 | 0.83 | ELANE (0.55) | BCL2MCL1MEN1KMT2ACDC25B | |
| SCHEMBL1197835 | 0.82 | MCL1 (0.64) | BCL2MCL1MEN1KMT2ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |