SCHEMBL7905176

SCHEMBL7905176

Cc1csc(-c2ccc(-c3ccc(-c4nc(C)cs4)cc3)cc2)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.58
CYP2E1 P05181 1/20 0.58
CYP2A6 P11509 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2B6 P20813 1/20 0.58
PDE10A Q9Y233 1/20 0.50
RAB9A P51151 4/20 0.48
NPC1 O15118 3/20 0.48
KDM4E B2RXH2 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
SREBF2 Q12772 1/20 0.48
AOC3 Q16853 2/20 0.48
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NOS1 P29475 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8198560 0.98 CYP3A4 (0.60) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL14438067 0.92 CYP3A4 (0.61) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL12180534 0.91 RAB9A (0.59) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL18725058 0.89 CYP3A4 (0.53) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL23367838 0.87 RAB9A (0.56) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL2092693 0.87 KDM4E (0.56) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL2094966 0.87 GFER (0.58) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL13680611 0.87 CYP3A4 (0.51) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL3182382 0.87 KDM4E (0.54) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6
SCHEMBL17795539 0.87 CYP3A4 (0.51) CYP3A4CYP2E1CYP2A6CYP2C9CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed