SCHEMBL7905202

SCHEMBL7905202

CCOC(=O)C(S)Cc1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.50
MME P08473 1/20 0.49
ACE P12821 1/20 0.49
CPA1 P15085 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
CTNNB1 P35222 1/20 0.49
KDM4E B2RXH2 1/20 0.48
APOBEC3A P31941 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
CDC25B P30305 2/20 0.47
TACR1 P25103 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CDC25A P30304 1/20 0.44
CDC25C P30307 1/20 0.44
CDYL Q9Y232 1/20 0.43
ATM Q13315 1/20 0.43
MMP9 P14780 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20678776 0.87 KMT2A (0.49) KMT2AMMEACECPA1ACE2
SCHEMBL7896757 0.87 ATM (0.50) MMEACECPA1ACE2CTNNB1
SCHEMBL6719502 0.85 CTNNB1 (0.59) KMT2AMMEACECPA1ACE2
SCHEMBL6176215 0.84 KMT2A (0.51) KMT2AMMEACECPA1ACE2
SCHEMBL3936305 0.82 KMT2A (0.50) KMT2ACTNNB1KDM4EAPOBEC3AAPOBEC3G
SCHEMBL8465002 0.82 KMT2A (0.50) KMT2ACTNNB1KDM4EAPOBEC3AAPOBEC3G
SCHEMBL10389809 0.82 CTNNB1 (0.52) KMT2AMMEACECPA1ACE2
SCHEMBL7262986 0.82 KMT2A (0.50) KMT2ACTNNB1KDM4EAPOBEC3AAPOBEC3G
SCHEMBL13821887 0.82 EPHX2 (0.51) KMT2ACTNNB1KDM4EALDH1A1HPGD
SCHEMBL7322093 0.82 CTNNB1 (0.60) KMT2AMMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235358-B1 COATING LAYERS OF EPOXY RESINS AND PHOTOCATIONIC CURING CATALTST WITH CATIONIC SULFUR ESTERS, SENSITIZERS OF THIOXANTHONES AND TITANIUM DIOXIDE PIGMENTS TOYO SEIKAN KAISHA, LTD. (JP) 2001-05-22 US disclosed