SCHEMBL7905209

SCHEMBL7905209

O=c1ccccc(-c2cccc3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.50
ACMSD Q8TDX5 1/20 0.50
CA12 O43570 3/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA9 Q16790 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALPL P05186 1/20 0.49
GAA P10253 1/20 0.49
EDNRB P24530 1/20 0.46
EDNRA P25101 1/20 0.46
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
PTPN1 P18031 1/20 0.44
POLB P06746 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29628903 0.85 MCL1 (0.53) MCL1ACMSDCA12CA1CA2
SCHEMBL14036308 0.85 MCL1 (0.53) MCL1ACMSDCA12CA1CA2
SCHEMBL16796022 0.81 MCL1 (0.50) MCL1ACMSDCA12CA1CA2
SCHEMBL316112 0.80 TNF (0.57) MCL1ACMSDCA12CA1CA2
SCHEMBL24816033 0.79 CA12 (0.56) MCL1ACMSDCA12CA1CA2
SCHEMBL29628965 0.79 CA12 (0.56) MCL1ACMSDCA12CA1CA2
SCHEMBL29892508 0.79 CA12 (0.56) MCL1ACMSDCA12CA1CA2
Hydrochloric Acid SCHEMBL2546050 0.78 TNF (0.55) MCL1ACMSDCA12CA1CA2
SCHEMBL69345 0.78 TNF (0.61) MCL1ACMSDCA12CA1CA2
SCHEMBL29399206 0.78 TNF (0.61) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed