SCHEMBL7905557

SCHEMBL7905557

Cc1cc(C)cc(-c2[nH]c3ccc(N)cc3c2CCN(CCCCc2ccc([N+](=O)[O-])cc2)Cc2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907197 0.86 GNRHR (0.44) GNRHR
SCHEMBL7911998 0.86 GNRHR (0.56) GNRHR
SCHEMBL6981787 0.85 GNRHR (0.51) GNRHR
SCHEMBL7908680 0.84 GNRHR (0.41) GNRHR
SCHEMBL7912488 0.84 GNRHR (0.42) GNRHR
SCHEMBL7907194 0.84 GNRHR (0.60) GNRHR
SCHEMBL7899429 0.84 GNRHR (0.41) GNRHR
SCHEMBL6985175 0.83 GNRHR (0.53) GNRHR
SCHEMBL8326584 0.82 GNRHR (0.43) GNRHR
SCHEMBL7908397 0.77 GNRHR (0.43) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197975-B1 7-AZABICYCLO(2.2.1)HEPTANE-7-CARBONYL-SUBSTITUTED 2-PHENYLINDOLE DERIVATIVES; SEXUAL DISORDERS; ANTICARCINOGENIC AGENTS MERCK & CO. , INC. 2001-03-06 US disclosed