Sugi Predict

Sugi Predict / Compounds / SCHEMBL7907194

SCHEMBL7907194

SCHEMBL7907194

Cc1cc(C)cc(-c2[nH]c3ccc(N)cc3c2CCN(CCCCc2ccc(NS(C)(=O)=O)cc2)Cc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GNRHR P30968 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911998 0.89 GNRHR (0.56) GNRHR
SCHEMBL7912485 0.85 GNRHR (0.51) GNRHR
SCHEMBL7911715 0.85 GNRHR (0.55) GNRHR
SCHEMBL7905557 0.84 GNRHR (0.42) GNRHR
SCHEMBL7899428 0.83 GNRHR (0.51) GNRHR
SCHEMBL7905608 0.82 GNRHR (0.82) GNRHR
SCHEMBL7907287 0.81 GNRHR (0.63) GNRHR
SCHEMBL6985175 0.81 GNRHR (0.53) GNRHR
SCHEMBL7907209 0.81 GNRHR (0.54) GNRHR
SCHEMBL8692405 0.77 GNRHR (0.55) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197975-B1 7-AZABICYCLO(2.2.1)HEPTANE-7-CARBONYL-SUBSTITUTED 2-PHENYLINDOLE DERIVATIVES; SEXUAL DISORDERS; ANTICARCINOGENIC AGENTS MERCK & CO. , INC. 2001-03-06 — — US disclosed
EP-0882040-A4 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO INC (US) 1999-02-10 — — EP disclosed
EP-0882040-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE Merck & Co., Inc. (US) 1998-12-09 — — EP disclosed
WO-1997021707-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO., INC. (US) 1997-06-19 — — WO disclosed