Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL468587 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL31108184 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL27916717 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL28054177 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL8366397 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL30253568 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL7085968 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL37647 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL28924405 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL3083 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207735-B1 | FLAME RETARDANT COMPRISING ETHYLENEDIAMINE-CONTAINING ZINC PHOSPHATE, METAL COMPOUND, 1,3,5-TRIAZINE DERIVATIVE AND/OR PHOSPHORUS-CONTAINING COMPOUND | TOSCH CORPORATION (JP) | 2001-03-27 | — | — | US | disclosed |
| US-5994435-A | CONTAINING REACTION PRODUCT OF ETHYLENEDIAMINE AND ZINC PHOSPHATE | TOSOH CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0921174-A1 | Flame retardant and flame retardant resin composition containing it | Tosoh Corporation (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0189632-B1 | SUPPORTED TRANSITION METAL SULFIDE PROMOTED MOLYBDENUM OR TUNGSTEN SULFIDE CATALYSTS AND THEIR USES FOR HYDROPROCESSING | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| EP-0189634-B1 | TRANSITION METAL SULFIDE PROMOTED MOLYBDENUM OR TUNGSTEN SULFIDE CATALYSTS AND THEIR USES FOR HYDROPROCESSING | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4795731-A | UPGRADING COORDINATION CATALYST | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| US-4755496-A | Supported transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4698145-A | Supported transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| US-4650563-A | HYDRODENITROGENIZATION, HYDRODESULFURIZATION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| EP-0189634-A1 | Transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| EP-0189632-A1 | Supported transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4091822-A | POLYDENTATE AMINE AND ZINC, IRON/II/, COPPER, OR NICKEL, COMPLEXING | LOEWS THEATRES, INC. (US) | 1978-05-30 | — | — | US | disclosed |