Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905716 | 1.00 | MAPK1 (0.42) | MAPK1CTSKCTSSCTSLCTSB | |
| SCHEMBL19700566 | 0.98 | MAPK1 (0.43) | MAPK1CTSKCTSSCTSLCTSB | |
| SCHEMBL25609899 | 0.98 | MAPK1 (0.43) | MAPK1CTSKCTSSCTSLCTSB | |
| SCHEMBL25609901 | 0.98 | MAPK1 (0.43) | MAPK1CTSKCTSSCTSLCTSB | |
| SCHEMBL16001425 | 0.76 | HTT (0.44) | MAPK1MEN1KMT2A | |
| SCHEMBL13492155 | 0.76 | HTT (0.44) | MAPK1MEN1KMT2A | |
| SCHEMBL16001429 | 0.76 | HTT (0.44) | MAPK1MEN1KMT2A | |
| SCHEMBL16001433 | 0.76 | HTT (0.44) | MAPK1MEN1KMT2A | |
| SCHEMBL7897780 | 0.76 | SMN1; SMN2 (0.33) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL7897784 | 0.76 | SMN1; SMN2 (0.33) | CTSKCTSSCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |