Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897780 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2CTSKUSP2CTSSCTSL | |
| SCHEMBL7907019 | 0.83 | HSD17B10 (0.45) | USP2 | |
| SCHEMBL7897554 | 0.80 | USP2 (0.47) | CTSKUSP2CTSLCTSB | |
| SCHEMBL7897551 | 0.80 | USP2 (0.47) | CTSKUSP2CTSLCTSB | |
| SCHEMBL7905716 | 0.76 | MAPK1 (0.42) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL7905711 | 0.76 | MAPK1 (0.42) | CTSKCTSSCTSLCTSBCTSH | |
| Butyl Alcohol SCHEMBL8589445 | 0.75 | USP2 (0.46) | CTSKUSP2CTSLCTSB | |
| SCHEMBL25609901 | 0.74 | MAPK1 (0.43) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL25609899 | 0.74 | MAPK1 (0.43) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL19700566 | 0.74 | MAPK1 (0.43) | CTSKCTSSCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |