SCHEMBL7905759

SCHEMBL7905759

CC(=O)CCC(C)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24083670 1.00
SCHEMBL10810758 0.86 TSHR (0.43)
SCHEMBL35490 0.81
Water SCHEMBL28240439 0.81 GABRP (0.50)
SCHEMBL18977900 0.80 TSHR (0.38)
SCHEMBL4448500 0.79
Hydrochloric Acid SCHEMBL7043007 0.79 GABRP (0.48)
SCHEMBL5050240 0.79 GABRP (0.48)
SCHEMBL30725511 0.79 GABRP (0.48)
SCHEMBL17389299 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5334721-A Reacting a methyl ketone and an alpha,beta-unsaturated nitrile in the presence of a basic catalyst; preparation of a 2-methyl-3,5-dialkylpyridine; cyclization; dehydrogenation STAMICARBON B.V. (NL) 1994-08-02 US claimed
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-23 US disclosed
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-23 US disclosed
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-08-22 US disclosed
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-08-22 US disclosed
US-20180141912-A1 VERSATILE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-05-24 US disclosed
WO-2017137984-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-08-17 WO disclosed
US-20070087447-A1 System and method of free radical initiated protein sequencing CALIFORNIA INSTITUTE OF TECHNOLOGY 2007-04-19 US disclosed
US-6219622-B1 Computational method for designing chemical structures having common functional characteristics UNIVERSITY OF GUELPH (CA) 2001-04-17 US disclosed
EP-0888591-A1 COMPUTATIONAL METHOD FOR DESIGNING CHEMICAL STRUCTURES HAVING COMMON FUNCTIONAL CHARACTERISTICS UNIVERSITY OF GUELPH (CA) 1999-01-07 EP disclosed
US-5699268-A Computational method for designing chemical structures having common functional characteristics UNIVERSITY OF GUELPH (CA) 1997-12-16 US disclosed
WO-1997036252-A1 COMPUTATIONAL METHOD FOR DESIGNING CHEMICAL STRUCTURES HAVING COMMON FUNCTIONAL CHARACTERISTICS UNIVERSITY OF GUELPH (CA) 1997-10-02 WO disclosed
EP-0437290-A1 Process for the preparation of 5-oxohexane nitriles and the compound 2,4-dimethyl-5-oxohexane nitrile DSM N.V. (NL) 1991-07-17 EP disclosed