Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872733 | 0.81 | TSHR (0.39) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7152228 | 0.81 | TSHR (0.39) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL14349076 | 0.80 | TSHR (0.42) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL8135367 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL1926225 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL16127309 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL15061127 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL22579171 | 0.77 | TSHR (0.39) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL29913745 | 0.76 | TSHR (0.42) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL18058807 | 0.76 | TSHR (0.39) | KDM4EALDH1A1TSHRRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197867-B1 | DINITRILE PROCESSING AIDS | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-03-06 | — | — | US | claimed |
| US-8809488-B2 | Carboxylated polymers of intrinsic microporosity (PIMs) with tunable gas transport properties | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2014-08-19 | — | — | US | disclosed |
| US-6197867-B1 | DINITRILE PROCESSING AIDS | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0965613-A1 | Rubber compositions containing organo-nitriles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |