Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503980 | 1.00 | ACHE (0.54) | ACHEESR1ESR2HTR1ALMNA | |
| SCHEMBL7909268 | 1.00 | ACHE (0.54) | ACHEESR1ESR2HTR1ALMNA | |
| SCHEMBL7907579 | 0.98 | ACHE (0.51) | ACHEESR1ESR2HTR1ALMNA | |
| SCHEMBL5493886 | 0.81 | ACHE (0.40) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL7906100 | 0.81 | ACHE (0.40) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL7909231 | 0.81 | ACHE (0.40) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL11763224 | 0.81 | ACHE (0.39) | ACHEESR1ESR2LMNAALDH1A1 | |
| SCHEMBL7907552 | 0.80 | PPARA (0.54) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL9818192 | 0.80 | PPARA (0.54) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL7908966 | 0.80 | PPARA (0.54) | ACHEESR1ESR2LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187493-B1 | CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE | KYOCERA MITA CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0738934-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |