Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869281 | 0.95 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL7787903 | 0.92 | TSHR (0.41) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Acrylic Acid SCHEMBL11775493 | 0.91 | TSHR (0.36) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL14740570 | 0.90 | TSHR (0.42) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL650597 | 0.90 | TSHR (0.42) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Ethylene SCHEMBL2050495 | 0.89 | TSHR (0.41) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Butadiene SCHEMBL9720053 | 0.87 | TSHR (0.40) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL2641211 | 0.87 | TSHR (0.43) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Methacrylic Acid SCHEMBL6275938 | 0.85 | TSHR (0.39) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL37916 | 0.85 | TSHR (0.47) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197289-B1 | Removal of biologically active agents | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6146771-A | Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |
| EP-1021216-A1 | PROCESS FOR MODIFIYING SURFACES USING THE REACTION PRODUCT OF A WATER-INSOLUBLE POLYMER AND A POLYALKLENE IMINE | Terumo Cardiovascular Systems Corporation (US) | 2000-07-26 | — | — | EP | disclosed |
| EP-0994745-A1 | REMOVAL OF BIOLOGICALLY ACTIVE AGENTS | Terumo Cardiovascular Systems Corporation (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001195-A1 | REMOVAL OF BIOLOGICALLY ACTIVE AGENTS | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001167-A1 | PROCESS FOR MODIFIYING SURFACES USING THE REACTION PRODUCT OF A WATER-INSOLUBLE POLYMER AND A POLYALKLENE IMINE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |