Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 11/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650597 | 0.96 | TSHR (0.42) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL14740570 | 0.96 | TSHR (0.42) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Ethylene SCHEMBL2050495 | 0.95 | TSHR (0.41) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Methacrylic Acid SCHEMBL6275938 | 0.91 | TSHR (0.39) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Butadiene SCHEMBL4557890 | 0.91 | TSHR (0.47) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL10565297 | 0.89 | THRB (0.50) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL27507777 | 0.88 | THRB (0.44) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Methacrylic Acid SCHEMBL8664308 | 0.87 | TSHR (0.41) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL7906178 | 0.87 | TSHR (0.36) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL7906177 | 0.87 | TSHR (0.38) | TSHRHPGDMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164434-A | Sulfide compound for thermal and/or oxidative stabilization of polymers | ROHM AND HAAS COMPANY (US) | 1992-11-17 | — | — | US | disclosed |