Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | MGAM | O43451 | 6/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.41 |
| ▸ | SI | P14410 | 6/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445611 | 0.85 | GAA (0.45) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL427465 | 0.85 | KCNMA1 (0.55) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL425552 | 0.84 | KMT2A (0.59) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL447802 | 0.82 | GAA (0.63) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL427449 | 0.77 | GLA (0.47) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL427308 | 0.77 | KMT2A (0.70) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7899312 | 0.75 | KMT2A (0.59) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL425440 | 0.74 | F12 (0.60) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL11358890 | 0.74 | KCNMA1 (0.57) | KMT2AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL11357460 | 0.71 | KCNMA1 (0.54) | KMT2AKDM4EALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |