Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898126 | 0.86 | PNP (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL21805968 | 0.69 | PNP (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL22143 | 0.69 | PNP (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL29733326 | 0.68 | PNP (0.41) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL9154825 | 0.67 | PNP (0.39) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL29456668 | 0.66 | HSD17B10 (0.44) | MAPTHIF1AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27844165 | 0.64 | PNP (0.37) | PNPMAPTCDK1CDK4CDK2 | |
| Phosphoric Acid SCHEMBL6461187 | 0.63 | PNP (0.36) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL30776984 | 0.63 | PNP (0.40) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL1271646 | 0.60 | CDK1 (0.56) | PNPMAPTCDK1CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218134-B1 | INTRODUCING LABELED SPECIFIC BINDING SUBSTANCE AND LIQUID TEST SAMPLE INTO MATRIX OF DEVICE, BINDING SUBSTANCE SPECIFICALLY COMPETES WITH ANALYTE FOR OTHER SPECIFIC BINDING SUBSTANCE, SIGNAL IS GENERATED WHICH CHANGES DISTRIBUTION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |