Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906287 | 1.00 | TBXAS1 (0.40) | TBXAS1CTSSFNTAFNTB | |
| SCHEMBL7906291 | 1.00 | TBXAS1 (0.40) | TBXAS1CTSSFNTAFNTB | |
| SCHEMBL7905160 | 0.89 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7906986 | 0.86 | — | — | |
| SCHEMBL7906976 | 0.86 | — | — | |
| SCHEMBL7897600 | 0.85 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL7897607 | 0.85 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL7905447 | 0.85 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL7903693 | 0.85 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL7903699 | 0.85 | FNTA (0.58) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |