Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650258 | 0.69 | KDM4E (0.43) | — | |
| SCHEMBL7906499 | 0.67 | SREBF2 (0.33) | PDE10A | |
| SCHEMBL18198922 | 0.64 | TYMS (0.41) | PDE10A | |
| SCHEMBL21029948 | 0.61 | ADORA2A (0.46) | — | |
| SCHEMBL5677317 | 0.59 | HMGCR (0.40) | — | |
| SCHEMBL6214177 | 0.58 | PDE4A (0.48) | — | |
| SCHEMBL15071229 | 0.58 | KDM4E (0.36) | — | |
| SCHEMBL9988127 | 0.58 | KDM4E (0.36) | — | |
| SCHEMBL3370732 | 0.58 | KDM4E (0.36) | — | |
| SCHEMBL8758380 | 0.57 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6193954-B1 | ADMINISTERING THERAPEUTICALLY EFFECTIVE AMOUNT OF DRUG DOPAMINE AGONIST, A PROPELLANT AND POLOXAME TO PATIENT | ABBOTT LABORATORIES | 2001-02-27 | — | — | US | disclosed |