SCHEMBL7906606

SCHEMBL7906606

C[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1OP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 16/20 0.52
P2RY4 P51582 9/20 0.52
DUT P33316 1/20 0.48
POLA1 P09884 1/20 0.47
P2RY14 Q15391 1/20 0.47
P2RY6 Q15077 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906610 1.00 P2RY2 (0.52) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL29431049 0.83 DUT (0.56) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL3226919 0.83 DUT (0.51) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL28015218 0.82 POLB (0.57) POLA1
SCHEMBL2811539 0.81 DUT (0.47) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL2811543 0.81 DUT (0.61) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL14913972 0.81 DUT (0.51) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL4348233 0.80 P2RY2 (0.51) P2RY2P2RY4DUTPOLA1P2RY6
SCHEMBL2811544 0.80 DUT (0.46) P2RY2P2RY4DUTPOLA1P2RY14
SCHEMBL4619792 0.79 DUT (0.50) P2RY2P2RY4DUTPOLA1P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194141-B1 DETECTING MODULATOR OF VIRAL PROPAGATION; INCUBATE VIRAL NUCLEOTIDE SEQUENCE MIXTURE WITH METALS, INCUBATE SECOND MIXTURE WITH MODULATOR, CALIBRATE AND COMPARE AMOUNT OF URIDINE INCORPORATED INTO TRANSCRIPTS IN BOTH MIXTURES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2001-02-27 US disclosed