Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871556 | 0.95 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL301354 | 0.91 | TSHR (0.37) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16178607 | 0.90 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL31127935 | 0.90 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1930958 | 0.90 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL17891351 | 0.90 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3189947 | 0.87 | TSHR (0.38) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9874027 | 0.86 | TSHR (0.34) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL11787519 | 0.85 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL30880869 | 0.83 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221988-B1 | NONAQUEOUS PROTECTIVE COATINGS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 2001-04-24 | — | — | US | disclosed |