SCHEMBL1930958

SCHEMBL1930958

C=CC(=O)OCCN(C)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 2/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 2/20 0.35
CA1 P00915 5/20 0.33
CA2 P00918 5/20 0.33
MMP1 P03956 5/20 0.33
MMP2 P08253 5/20 0.33
MMP9 P14780 5/20 0.33
MMP8 P22894 5/20 0.33
MMP13 P45452 5/20 0.33
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16178607 1.00 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL31127935 1.00 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17891351 1.00 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL301354 0.99 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3189947 0.95 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9871556 0.92 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7906779 0.90 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7906796 0.87 TSHR (0.33) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL30424942 0.86 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5399535 0.85 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110291174-B Tackifying proppant for carbon dioxide-based fracturing fluid and preparation and application methods thereof 沙特阿拉伯石油公司 2022-04-26 CN claimed
US-10131833-B2 Self-suspending modified proppant system for carbon dioxide based fracturing fluids ARAMCO SERVICES COMPANY (US) 2018-11-20 US claimed
US-10131834-B2 Self-suspending modified proppant system for carbon dioxide based fracturing fluids ARAMCO SERVICES COMPANY 2018-11-20 US claimed
US-10119068-B2 Viscosifying modified proppant system for carbon dioxide based fracturing fluids SAUDI ARABIAN OIL COMPANY (SA) 2018-11-06 US claimed
US-10106733-B2 Viscosifying modified proppant system for carbon dioxide based fracturing fluids SAUDI ARABIAN OIL COMPANY (SA) 2018-10-23 US claimed
US-10066155-B1 Viscosifying proppants for use in carbon dioxide-based fracturing fluids and methods of making and use thereof SAUDI ARABIAN OIL COMPANY (SA) 2018-09-04 US claimed
EP-3053751-B1 A PLANOGRAPHIC PRINTING SYSTEM AND A PLANOGRAPHIC PRINTING METHOD INST CHEMISTRY CAS (CN) 2018-04-18 EP claimed
EP-3053751-A1 A PLANOGRAPHIC PRINTING SYSTEM AND A PLANOGRAPHIC PRINTING METHOD Institute of Chemistry, Chinese Academy of Sciences (CN) 2016-08-10 EP claimed
US-20160193827-A1 PLANOGRAPHIC PRINTING SYSTEM AND A PLANOGRAPHIC PRINTING METHOD INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2016-07-07 US claimed
US-20160193861-A1 PRINTING PLATE AND THE PREPARATION METHOD THEREOF AND A PRINTING METHOD INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2016-07-07 US claimed
EP-0960143-A1 METHOD OF MAKING FLUOROPOLYMERS The University of North Carolina at Chapel Hill (US) 1999-12-01 EP claimed
US-5860467-A Use of CO2 -soluble materials in making molds THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-01-19 US claimed
WO-1998034967-A1 METHOD OF MAKING FLUOROPOLYMERS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-08-13 WO claimed
WO-1998026886-A1 USE OF CO2-SOLUBLE MATERIALS AS TRANSIENT SPACERS, TEMPLATES, ADHESIVES, BINDERS, COATINGS AND MOLDS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-06-25 WO claimed
US-5739223-A POLYMERIZATION REACTION MIXTURE COMPRISING FLUOROMONOMER IN CARBON DIOXIDE FLUID SOLVENT, POLYMERIZATION INITIATOR THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-04-14 US claimed
EP-0773016-B1 Topical composition containing a combination of a silicon grafted polymer with a non-silicon backbone and a non-silicon grafted polysiloxan polymer OREAL (FR) 1998-04-01 EP claimed
US-5496901-A SOLUBILIZING MONOMER IN A CARBON DIOXIDE FLUID SOLVENT AND POLYMERIZING UNIVERSITY OF NORTH CAROLINA (US) 1996-03-05 US claimed
EP-0638095-A1 METHOD OF MAKING FLUOROPOLYMERS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-02-15 EP claimed
WO-1993020116-A1 METHOD OF MAKING FLUOROPOLYMERS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1993-10-14 WO claimed
US-4972037-A ACRYLATED POLYSILOXANES GRAFTED FLUOROPOLYMERS AS ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-20 US claimed