Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246326 | 1.00 | EPHX2 (0.46) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1245712 | 0.96 | PPM1B (0.45) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1297188 | 0.94 | ALDH1A1 (0.47) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1297197 | 0.93 | EPHX2 (0.51) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL7910485 | 0.93 | PPM1B (0.47) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL7910526 | 0.93 | PPM1B (0.47) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1296801 | 0.93 | EPHX2 (0.42) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1296845 | 0.93 | PPM1B (0.47) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1296325 | 0.93 | EPHX2 (0.45) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL8695709 | 0.92 | PPM1B (0.51) | EPHX2PPM1BPTPN1PPP1CCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210956-B1 | USED AS CHIRAL PRECURSORS FOR NON-NATURALLY OCCURING AMINO ACIDS AND POLYESTER; CONTACTING A 1,3-CYCLOHEXANEDICARBOXYLIC ACID DIESTER DERIVATIVE WITH A LIPASE CAPABLE OF CONVERTING IT UNDER AQUEOUS CONDITIONS | EASTMAN CHEMICAL COMPANY | 2001-04-03 | — | — | US | disclosed |
| US-6028213-A | BY CONTACTING WITH A LIPASE UNDER AQUEOUS CONDITIONS TO ENANTIOSELECTIVELY PRODUCE THE ACTIVATOR | EASTMAN CHEMICAL COMPANY (US) | 2000-02-22 | — | — | US | disclosed |