Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907275 | 1.00 | RARB (0.40) | RARBCYP2C9CYP3A4SPHK1FASN | |
| SCHEMBL9665276 | 0.97 | RARB (0.43) | RARBCYP2C9CYP3A4SPHK1FASN | |
| SCHEMBL9664439 | 0.94 | RARB (0.36) | RARBCYP2C9CYP3A4SPHK1FASN | |
| SCHEMBL9664446 | 0.94 | RARB (0.36) | RARBCYP2C9CYP3A4SPHK1FASN | |
| SCHEMBL9664451 | 0.94 | RARB (0.36) | RARBCYP2C9CYP3A4SPHK1FASN | |
| SCHEMBL16258050 | 0.93 | CYP2C9 (0.39) | RARBCYP2C9CYP3A4SPHK1APP | |
| SCHEMBL9662994 | 0.93 | RARB (0.41) | RARBCYP2C9CYP3A4SPHK1FASN | |
| SCHEMBL16117388 | 0.93 | CYP2C9 (0.39) | RARBCYP2C9CYP3A4SPHK1APP | |
| SCHEMBL2604712 | 0.93 | CYP2C9 (0.39) | RARBCYP2C9CYP3A4SPHK1APP | |
| SCHEMBL8407315 | 0.93 | CYP2C9 (0.41) | RARBCYP2C9CYP3A4SPHK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570024-B1 | FAST SWITCHING LIQUID CRYSTAL COMPOSITIONS FOR USE IN BISTABLE LIQUID CRYSTAL DEVICES | MERCK PATENT GMBH (DE) | 2007-08-01 | — | — | EP | disclosed |
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| EP-0394417-B2 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0438547-B2 | SUPER-TWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-07-07 | — | — | EP | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0494368-B1 | Supertwist liquid crystal display | MERCK PATENT GMBH (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0481293-B1 | Supertwist liquid crystal display | MERCK PATENT GMBH (DE) | 1996-06-05 | — | — | EP | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0438547-B1 | SUPER-TWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0366985-B1 | Super twist liquid crystal display | MERCK PATENT GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0158137-A2 | Pyrimidines | MERCK PATENT GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |
| US-4545922-A | Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0149238-A2 | Nitrogen containing heterocycles | MERCK PATENT GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |
| US-4510069-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-09 | — | — | US | disclosed |
| EP-0127816-A2 | Trans-Decalincarbonitriles | MERCK PATENT GmbH (DE) | 1984-12-12 | — | — | EP | disclosed |
| US-4478740-A | Benzonitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0051738-B1 | CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4415470-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0087056-A1 | Benzonitriles | MERCK PATENT GmbH (DE) | 1983-08-31 | — | — | EP | disclosed |
| EP-0051738-A1 | Cyclohexyl-biphenyl derivatives that contain fluor, dielectrics containing them and electro-optical indicating element | MERCK PATENT GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |