Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407319 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL2604712 | 0.93 | CYP2C9 (0.39) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL16258050 | 0.93 | CYP2C9 (0.39) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL16117388 | 0.93 | CYP2C9 (0.39) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL7907282 | 0.93 | RARB (0.40) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL7907275 | 0.93 | RARB (0.40) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL16117390 | 0.92 | CYP2C9 (0.39) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL10943958 | 0.92 | SPHK1 (0.42) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL9775767 | 0.92 | SPHK1 (0.48) | CYP2C9CYP3A4SPHK1RARBAPP | |
| SCHEMBL9775763 | 0.92 | SPHK1 (0.48) | CYP2C9CYP3A4SPHK1RARBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438547-B2 | SUPER-TWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-07-07 | — | — | EP | disclosed |
| EP-0481293-B1 | Supertwist liquid crystal display | MERCK PATENT GMBH (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0481293-A2 | Supertwist liquid crystal display | MERCK PATENT GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0117631-B1 | DISUBSTITUTED ETHANES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-04-29 | — | — | EP | disclosed |
| US-4545922-A | Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0074608-B1 | LIQUID CRYSTAL HALOGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION, DIELECTRIC AND DECTROOPTICAL DISPLAY ELEMENT CONTAINING THEM | MERCK PATENT GmbH (DE) | 1985-07-03 | — | — | EP | disclosed |
| US-4490305-A | Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-12-25 | — | — | US | disclosed |
| EP-0051738-B1 | CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4415470-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0074608-A2 | Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them | MERCK PATENT GmbH (DE) | 1983-03-23 | — | — | EP | disclosed |
| EP-0051738-A1 | Cyclohexyl-biphenyl derivatives that contain fluor, dielectrics containing them and electro-optical indicating element | MERCK PATENT GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |