Sugi Predict

Sugi Predict / Compounds / SCHEMBL7907287

SCHEMBL7907287

SCHEMBL7907287

Cc1cc(C)cc(-c2[nH]c3ccc(N)cc3c2CCC(NCCCCc2ccc(NS(C)(=O)=O)cc2)c2ccccc2)c1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GNRHR P30968 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7905608 0.84 GNRHR (0.82) GNRHR
SCHEMBL7907194 0.81 GNRHR (0.60) GNRHR
SCHEMBL7907209 0.74 GNRHR (0.54) GNRHR
SCHEMBL7908807 0.72 GNRHR (0.75) GNRHR
SCHEMBL8694427 0.72 GNRHR (0.56) GNRHR
SCHEMBL7908406 0.72 GNRHR (0.41) GNRHR
SCHEMBL8692401 0.72 GNRHR (0.56) GNRHR
SCHEMBL8693238 0.71 GNRHR (0.73) GNRHR
SCHEMBL7911998 0.71 GNRHR (0.56) GNRHR
SCHEMBL6983634 0.71 TACR1 (0.39) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197975-B1 7-AZABICYCLO(2.2.1)HEPTANE-7-CARBONYL-SUBSTITUTED 2-PHENYLINDOLE DERIVATIVES; SEXUAL DISORDERS; ANTICARCINOGENIC AGENTS MERCK & CO. , INC. 2001-03-06 — — US disclosed
EP-0882040-A4 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO INC (US) 1999-02-10 — — EP disclosed
EP-0882040-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE Merck & Co., Inc. (US) 1998-12-09 — — EP disclosed
WO-1997021707-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO., INC. (US) 1997-06-19 — — WO disclosed