SCHEMBL7907369

SCHEMBL7907369

CC(C)([O])Cc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
TDP1 Q9NUW8 1/20 0.48
CYP2C9 P11712 2/20 0.48
ACP3 P15309 1/20 0.47
SSTR4 P31391 1/20 0.46
NQO2 P16083 1/20 0.45
NR1I2 O75469 1/20 0.44
LMNA P02545 1/20 0.44
ADRA2A P08913 1/20 0.44
ACHE P22303 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
KCNH2 Q12809 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
HPGD P15428 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8851072 0.84 CYP2C19 (0.50) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL31675157 0.83 CYP2D6 (0.53) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL11586023 0.83 CYP2D6 (0.53) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL4814074 0.82 CYP2D6 (0.52) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL7370145 0.81 CYP1A2 (0.47) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL2754934 0.80 CYP2D6 (0.50) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL808870 0.80 TDP1 (0.53) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL6437231 0.80 CYP2C19 (0.50) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL17488720 0.80 CYP2D6 (0.50) CYP2C19CYP1A2CYP2D6TDP1CYP2C9
SCHEMBL6645801 0.80 CYP2D6 (0.50) CYP2C19CYP1A2CYP2D6TDP1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211397-B1 CHLORINATION OF PHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
CN-1186434-A Pharmaceutical composition containing protease inhibitor and monoglyceride HOFFMANN LA ROCHE (US) 1998-07-01 CN disclosed
EP-0603225-B1 PROCESS FOR PRODUCING alpha-CHLOR-METHYLEN-TRIORGANYLPHOSPHORANE DERIVATES BASF AG (DE) 1997-06-04 EP disclosed
WO-1993005053-A1 PROCESS FOR PRODUCING α-CHLOR-METHYLEN-TRIORGANYLPHOSPHORANE DERIVATES BASF AKTIENGESELLSCHAFT (DE) 1993-03-18 WO disclosed