Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907380 | 1.00 | TLR4 (0.41) | TLR4CES2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8015863 | 0.89 | CYP1A2 (0.33) | TLR4CYP2C9MAPTMEN1KMT2A | |
| SCHEMBL8736465 | 0.89 | TLR4 (0.39) | TLR4 | |
| SCHEMBL8736462 | 0.89 | TLR4 (0.39) | TLR4 | |
| SCHEMBL9352225 | 0.89 | MAOA (0.36) | TLR4CYP2C9MAPTMAPK1 | |
| SCHEMBL8217702 | 0.89 | TLR4 (0.42) | TLR4CES2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8037716 | 0.86 | TLR4 (0.36) | TLR4CYP2C9 | |
| SCHEMBL8049846 | 0.84 | TLR4 (0.36) | TLR4 | |
| SCHEMBL9351068 | 0.84 | TLR4 (0.36) | TLR4MAPTMAPK1 | |
| SCHEMBL9355160 | 0.83 | MAOB (0.35) | TLR4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| EP-0394417-B2 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0394417-B1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0366985-B1 | Super twist liquid crystal display | MERCK PATENT GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0394417-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1990-10-31 | — | — | EP | disclosed |
| WO-1990004622-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-05-03 | — | — | WO | disclosed |