Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL6535226 | 0.83 | HTT (0.51) | ARHTTHIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL15348 | 0.82 | HTT (0.56) | ARHTTHIF1AKMT2ASMN1; SMN2 | |
| Urethane SCHEMBL4370098 | 0.80 | AR (0.47) | ARHTTHIF1APPARDKMT2A | |
| SCHEMBL7907432 | 0.80 | AR (0.54) | ARHTTHIF1APPARDKMT2A | |
| SCHEMBL16437164 | 0.79 | SMN1; SMN2 (0.39) | ARHTTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL22193643 | 0.79 | HTT (0.52) | ARHTTHIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL5954197 | 0.78 | MEN1 (0.42) | ARHTTHIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL9510686 | 0.78 | HTT (0.47) | ARHTTHIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL203601 | 0.76 | SMN1; SMN2 (0.49) | ARHTTHIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL5187575 | 0.76 | HTT (0.46) | ARHTTHIF1AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204302-B1 | INCLUDES (A) 1-ARYL-2-ALKYL-1,2-ETHANEDIONE AND (B) A RIGID 1,2-DIONE | BISCO, INC. | 2001-03-20 | — | — | US | claimed |
| US-6204302-B1 | INCLUDES (A) 1-ARYL-2-ALKYL-1,2-ETHANEDIONE AND (B) A RIGID 1,2-DIONE | BISCO, INC. | 2001-03-20 | — | — | US | disclosed |