SCHEMBL9510686

SCHEMBL9510686

C=C(C)COC(C)COc1ccc(C(C)(C)c2ccc(OCC(C)OCC(=C)C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.47
HIF1A Q16665 2/20 0.47
AR P10275 2/20 0.46
KMT2A Q03164 6/20 0.40
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 5/20 0.38
TP53 P04637 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
CYP1A2 P05177 1/20 0.38
PPARG P37231 1/20 0.38
KDM4E B2RXH2 6/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
GAA P10253 1/20 0.36
PSMB1 P20618 1/20 0.35
PSMB5 P28074 1/20 0.35
PSMB2 P49721 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3899185 0.91 HTT (0.38) HTTHIF1AARKMT2AMEN1
SCHEMBL4625642 0.82 HTT (0.54) HTTHIF1AARKMT2AALDH1A1
SCHEMBL31316454 0.81 LMNA (0.53) HIF1AKMT2AALDH1A1MEN1MAPT
SCHEMBL30537232 0.81 AR (0.50) HTTHIF1AARKMT2AALDH1A1
SCHEMBL4198618 0.81 AR (0.50) HTTHIF1AARKMT2AALDH1A1
SCHEMBL203601 0.81 SMN1; SMN2 (0.49) HTTHIF1AARKMT2AALDH1A1
SCHEMBL12082206 0.80 HIF1A (0.54) HTTHIF1AARKMT2AALDH1A1
SCHEMBL59812 0.79 HTT (0.36) HTTHIF1AARKMT2AALDH1A1
SCHEMBL31316457 0.79 LMNA (0.50) HIF1AKMT2AALDH1A1MEN1MAPT
SCHEMBL15348 0.78 HTT (0.56) HTTHIF1AARKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514791-B2 Aesthetic dental filling material having high curing depth IVOCLAR VIVADENT AG (LI) 2026-01-06 US claimed
US-20250352435-A1 AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH IVOCLAR VIVADENT AG (LI) 2025-11-20 US claimed
US-12083194-B2 Dental materials based on polymerizable thiourea derivatives IVOCLAR VIVADENT AG (LI) 2024-09-10 US claimed
US-12043683-B2 Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives IVOCLAR VIVADENT AG (LI) 2024-07-23 US claimed
EP-4094748-B1 DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH OLIGOMERIC CUMOLHYDROPEROXIDE DERIVATIVES IVOCLAR VIVADENT AG (LI) 2023-09-20 EP claimed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US claimed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US claimed
EP-4032521-B1 DENTAL MATERIAL FOR THE PRODUCTION OF TEMPORARY CROWNS AND BRIDGES IVOCLAR VIVADENT AG (LI) 2023-03-01 EP claimed
US-20230059534-A1 AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH IVOCLAR VIVADENT AG (LI) 2023-02-23 US claimed
US-20230002531-A1 Dental Materials Based On Redox Systems With Oligomeric Cumene Hydroperoxide Derivatives UNIVERSITÉ MONTPELLIER (FR) 2023-01-05 US claimed
US-20200253837-A1 Dental Materials Based On Redox Systems With Low-Odour Cumene Hydroperoxide Derivatives IVOCLAR VIVADENT AG (LI) 2020-08-13 US claimed
EP-3692976-A1 DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH LOW ODOR CUMOLHYDE-HYDROPEROXIDE DERIVATIVES Ivoclar Vivadent AG (LI) 2020-08-12 EP claimed
EP-3692975-A1 DENTAL MATERIALS WITH IMPROVED SETTING Ivoclar Vivadent AG (LI) 2020-08-12 EP claimed
EP-3692974-A1 DENTAL MATERIALS WITH IMPROVED MECHANICAL CHARACTERISTICS Ivoclar Vivadent AG (LI) 2020-08-12 EP claimed
EP-3659575-A1 PHOTOPOLYMERISABLE DENTAL COMPOSITES WITH FAST CURING AND LOW SHRINKAGE STRESS Ivoclar Vivadent AG (LI) 2020-06-03 EP claimed
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS IVOCLAR VIVADENT AG (LI) 2020-05-28 US claimed
US-20200054423-A1 Monochromatic Dental Shaped Article And Blank For Making Dental Restorations IVOCLAR VIVADENT AG (LI) 2020-02-20 US claimed
EP-2987480-B1 Photocurable dental composites with increasing opacity IVOCLAR VIVADENT AG (LI) 2019-06-19 EP claimed
EP-3375429-A1 MONOCHROMATIC DENTAL MOLDED ARTICLE AND BLANK FOR THE PRODUCTION OF DENTAL RESTORATIONS Ivoclar Vivadent AG (LI) 2018-09-19 EP claimed
EP-2987480-A1 Photocurable dental composites with increasing opacity Ivoclar Vivadent AG (LI) 2016-02-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress MMAB, ALAD, SULT1E1 HTT 439/4885HIF1A 739/4885AR 3613/4885
US-20230002531-A1 Dental Materials Based On Redox Systems With Oligomeric Cumene Hydroperoxide Derivatives CBR3, NR1H3, NR1I3 HTT 2557/4885HIF1A 1776/4885AR 863/4885
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress MMAB, ALAD, SULT1E1 HTT 439/4885HIF1A 739/4885AR 3613/4885
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS MMAB, ALAD, SULT1E1 HTT 439/4885HIF1A 739/4885AR 3613/4885
US-20230059534-A1 AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH CAD, RAD51, REV1 HTT 608/4885HIF1A 123/4885AR 1336/4885
US-12083194-B2 Dental materials based on polymerizable thiourea derivatives TAS2R10, PAM, HBG1 HTT 574/4885HIF1A 586/4885AR 2689/4885
US-12043683-B2 Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives CBR3, NR1H3, NR1I3 HTT 2557/4885HIF1A 1776/4885AR 863/4885
US-20200253837-A1 Dental Materials Based On Redox Systems With Low-Odour Cumene Hydroperoxide Derivatives GPX4, GPX1, AOX1 HTT 2074/4885HIF1A 367/4885AR 3706/4885
US-20250352435-A1 AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH CAD, REV1, RAD51 HTT 565/4885HIF1A 142/4885AR 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.