Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901210 | 0.88 | PARP15 (0.45) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7914316 | 0.82 | MAOB (0.66) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7900858 | 0.82 | PARP15 (0.51) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7908116 | 0.80 | CA12 (0.51) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7907977 | 0.79 | PARP15 (0.48) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7910883 | 0.76 | KDM4E (0.47) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7901116 | 0.75 | PARP15 (0.43) | PARP15PARP10PARP3MAOB | |
| SCHEMBL7900860 | 0.75 | — | — | |
| SCHEMBL7900862 | 0.75 | — | — | |
| SCHEMBL7900864 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |