Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 7/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 9/20 | 0.40 |
| ▸ | FPR1 | P21462 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947295 | 0.89 | F9 (0.42) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL12546666 | 0.89 | F9 (0.42) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL1947290 | 0.89 | F9 (0.42) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL12570020 | 0.87 | F9 (0.48) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL7905366 | 0.84 | F9 (0.44) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL12546579 | 0.84 | F9 (0.44) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL12787101 | 0.82 | F9 (0.49) | F9FPR2FPR1HDAC1HDAC8 | |
| SCHEMBL1950528 | 0.80 | FPR2 (0.41) | F9FPR2FPR1 | |
| SCHEMBL1950529 | 0.80 | FPR2 (0.41) | F9FPR2FPR1 | |
| SCHEMBL1949488 | 0.80 | F9 (0.42) | F9FPR2FPR1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |