SCHEMBL7907506

SCHEMBL7907506

C=CCc1ccc2c(c1C(=O)O)Nc1ccccc1S2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 13/20 0.42
GAA P10253 7/20 0.42
MAPT P10636 7/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALOX15 P16050 3/20 0.42
SNCA P37840 2/20 0.42
CYBB P04839 2/20 0.42
NOX3 Q9HBY0 2/20 0.42
NOX4 Q9NPH5 2/20 0.42
APP P05067 1/20 0.42
POLB P06746 3/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MCL1 Q07820 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
BCHE P06276 2/20 0.39
ACHE P22303 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7196398 0.80 NOX1 (0.44) NOX1GAAMAPTMEN1KMT2A
SCHEMBL246327 0.78 NOX1 (0.48) NOX1GAAMAPTMEN1KMT2A
SCHEMBL9281420 0.74 NOX1 (0.43) NOX1GAAMAPTMEN1KMT2A
SCHEMBL11372104 0.73 NOX1 (0.38) NOX1GAAMAPTMEN1KMT2A
SCHEMBL5411776 0.73 ALOX5 (0.57) NOX1GAAMAPTMEN1KMT2A
SCHEMBL1078781 0.71 NOX1 (0.43) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL9483121 0.70 NOX1 (0.63) NOX1GAAMAPTMEN1KMT2A
SCHEMBL28763174 0.70 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL293434 0.69 ALOX5 (0.54) NOX1GAAMAPTMEN1KMT2A
SCHEMBL31491519 0.69 NOX1 (0.74) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022264906-A1 PRIMER COMPOSITION FOR INORGANIC OXIDE VAPOR DEPOSITION, CURED PRODUCT AND MULTILAYER BODY DIC株式会社 2022-12-22 WO disclosed
EP-3130478-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2020-10-28 EP disclosed
US-20180304692-A1 FIBER FOR RUBBER REINFORCEMENT, RUBBER-FIBER COMPOSITE, AND PNEUMATIC TIRE USING SAME BRIDGESTONE CORPORATION (JP) 2018-10-25 US disclosed
US-20180297407-A1 FIBER FOR RUBBER REINFORCEMENT, RUBBER-FIBER COMPOSITE, AND PNEUMATIC TIRE USING SAME BRIDGESTONE CORPORATION (JP) 2018-10-18 US disclosed
US-20170028793-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2017-02-02 US disclosed
US-6189322-B1 Refrigerant-circulating system, and refrigerant compressor and refrigeration cycle employing the refrigerant compressor MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2001-02-20 US disclosed
EP-0738859-B1 Refrigeration system using hydrofluorocarbon refrigerant MITSUBISHI ELECTRIC CORP (JP) 2000-05-31 EP disclosed
EP-0743496-B1 Refrigeration system using hydrofluorocarbon refrigerant MITSUBISHI ELECTRIC CORP (JP) 2000-05-31 EP disclosed
EP-0738858-B1 Method of assembling refrigeration system using hydrofluorocarbon refrigerant MITSUBISHI ELECTRIC CORP (JP) 2000-05-31 EP disclosed
CN-1234429-A Refrigerant circulation system, refrigerant compressor and refrigeration circulation using said refrigrant compressor MITSUBISHI ELECTRIC CORP (JP) 1999-11-10 CN disclosed
EP-0743496-A2 Refrigeration system using hydrofluorocarbon refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1996-11-20 EP disclosed
EP-0738859-A2 Refrigeration system using hydrofluorocarbon refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1996-10-23 EP disclosed
EP-0738858-A2 Method of assembling refrigeration system using hydrofluorocarbon refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1996-10-23 EP disclosed
US-5531080-A Refrigerant circulating system MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1996-07-02 US disclosed
EP-0714973-A1 Refrigerating machine oil composition and compressor using the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1996-06-05 EP disclosed
US-5419144-A Refrigeration device using hydrofluorocarbon refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1995-05-30 US disclosed
US-5364900-A Metal oxides, hindered phenol and amine stabilizers ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-11-15 US disclosed
EP-0622445-A1 Refrigerant circulating system MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1994-11-02 EP disclosed
US-5355695-A Refrigeration device using hydrofluorocarbon refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1994-10-18 US disclosed
EP-0600131-A1 Refrigeration device using hydrofluorocarbon refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1994-06-08 EP disclosed